Software Downloads

Sysinternals.com - Excellent freeware utilities
Nirsoft.net - More great freeware utilities
Download.com - Software portal site
Tucows.com - Software portal site

Spyware and Virus Removal Freeware

Ad-aware Personal - Spyware removal
Spybot-S&D - Spyware removal and prevention
Microsoft AntiSpyware - Spyware removal and prevention
SpywareBlaster - Spyware prevention
AVG Anti-Virus Free Edition - Anti-virus with realtime protection

Hardware and Software Reviews

Anandtech - Reviews on various computing topics
PCPerspective.com - Hardware reviews
Tom's Hardware - Reviews on various computing topics

Computer Help

HelpWithWindows.com - Windows XP Tips
TweakXP.com - Windows XP Articles & Tweaks
Winforums - A large forum for computer help
Annoyances.org - Assistance for Windows Problems

Updates

Microsoft Update
Windows Updates - for when IE doesn't work

Miscellaneous

DAL.net - The DALnet IRC Network
Pasting sites - from wikipedia